Contraindicated in:
Use Cautiously in:
CV: hypertension, CARDIAC ARREST, MI.
Derm: impaired wound healing.
Endo: hypothyroidism.
F and E: hyponatremia.
GI: diarrhea, GI OBSTRUCTION/PERFORATION, worsened cirrhosis/hepatorenal syndrome.
GU: ↓ fertility (females), nephrotic syndrome, proteinuria.
Hemat: bleeding, neutropenia.
Neuro: encephalopathy, headache, POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME (PRES), STROKE.
Misc: INFUSION-RELATED REACTIONS.
Gastric Cancer or Hepatocellular Carcinoma
NonSmall Cell Lung Cancer
Colorectal Cancer
Therapeutic Classification: antineoplastics
Pharmacologic Classification: vascular endothelial growth factor antagonists
Absorption: IV administration results in complete bioavailability.
Distribution: Minimally distributed to tissues.
Metabolism/Excretion: Unknown.
Half-life: Unknown.
NDC Code*