F and E: electrolyte abnormalities (chronic use or dependence).
GI: cramping, diarrhea, nausea.
GU: pink-red or brown-black discoloration of urine.
Misc: laxative dependence.
Larger doses have been used to treat/prevent opioid-induced constipation. Consult labeling of individual OTC products for more specific dosing information
- PO (Adults): 17.250 mg 12 times daily.
- PO (Children 1217 yr): 17.626.4 mg 12 times daily.
- PO (Children 611 yr): 8.813.2 mg 12 times daily.
- PO (Children 26 yr): 4.46.6 mg 12 times daily.
Therapeutic Classification: laxatives
Pharmacologic Classification: stimulant laxatives
Absorption: Minimally absorbed following oral administration.
Distribution: Unknown.
Metabolism/Excretion: Unknown.
Half-life: Unknown.
(laxative effect)
May take as long as 24 hr.