ter-AY-zoe-sin 
Contraindicated in:
Use Cautiously in:
CV: first-dose orthostatic hypotension, arrhythmias, chest pain, palpitations, peripheral edema, tachycardia.
Derm: pruritus.
EENT: nasal congestion, blurred vision, conjunctivitis, intraoperative floppy iris syndrome, sinusitis.
GI: nausea, abdominal pain, diarrhea, dry mouth, vomiting.
GU: erectile dysfunction, urinary frequency.
Metab: weight gain.
MS: arthralgia, back pain, extremity pain.
Neuro: dizziness, headache, weakness, drowsiness, nervousness., paresthesia.
Resp: dyspnea.
Misc: fever.
Drug-Drug:
Hypertension
Therapeutic Classification: antihypertensives
Pharmacologic Classification: peripherally acting antiadrenergics
Absorption: Well absorbed after oral administration.
Distribution: Unknown.
Metabolism/Excretion: 50% metabolized by the liver. 10% excreted unchanged by the kidneys. 20% excreted unchanged in feces. 40% eliminated in bile.
Half-life: 12 hr.
| ROUTE | ONSET† | PEAK‡ | DURATION† |
|---|---|---|---|
| PO-hypertension | 15 min | 6–8 wk | 24 hr |
| PO-BPH | 2–6 wk | unknown | unknown |
†After single dose.
‡After multiple oral dosing.
NDC Code*