lor-A-ta-deen 
Contraindicated in:
Use Cautiously in:
Derm: photosensitivity, rash.
EENT: blurred vision.
GI: GI upset, dry mouth.
Metab: weight gain.
Neuro: confusion, drowsiness (rare), paradoxical excitation.
Drug-Drug:
Drug-Natural Products:
(Generic available)
Renal Impairment
Hepatic Impairment
Therapeutic Classification: allergy, cold and cough remedies
Pharmacologic Classification: antihistamines
Absorption: Rapidly absorbed after oral administration (80%).
Distribution: Unknown.
Protein Binding: Loratadine: 97%; descarboethoxyloratadine: 73–77%.
Metabolism/Excretion: Rapidly and extensively metabolized during first pass through the liver. Much is converted to descarboethoxyloratadine, an active metabolite.
Half-life: Loratadine: 8.4 hr; descarboethoxyloratadine: 28 hr.
NDC Code*