Contraindicated in:
Use Cautiously in:
CNS: headache, intracranial hypertension.
CV: peripheral edema.
Endo: hyperglycemia, hypothyroidism, insulin resistance.
GI: PANCREATITIS.
Hemat: eosinophilia.
Local: pain at injection site, local lipoatrophy or lipodystrophy with subcutaneous use.
MS: arthralgia.
Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA).
Drug-Drug:
Adult Growth Hormone Deficiency
Pediatric Growth Hormone Deficiency
Growth Failure Associated with Prader-Willi or Turner Syndrome
Short Stature Born Small for Gestational Age
Idiopathic Short Stature
Absorption: Well absorbed.
Distribution: Localize to highly perfused organs (liver, kidneys).
Metabolism/Excretion: Broken down in renal cells to amino acids that are recirculated; some liver metabolism.
Half-life: Subcut 2.52.8 hr.