mineral oil

section name header

Indications ⬇

REMS

Used to soften impacted feces in the management of constipation.

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Hypersensitivity
Children <6 yr (oral)
Children <2 yr (rect).

Use Cautiously in:

Children or debilitated patients (increased risk of lipid pneumonia)
Geri: Appears on Beers list due to increased risk of aspiration resulting in lipid pneumonia and other adverse effects
OB: Chronic use during pregnancy decreases absorption of fat-soluble vitamins and may cause hypoprothrombinemia in newborn.

Adv. Reactions/Side Effects ⬆ ⬇

Resp: lipid pneumonia.

GI: diarrhea, anal irritation, rectal seepage of mineral oil.

Interactions ⬆ ⬇

Drug-Drug:

Decreases absorption of fat-soluble vitamins (A, D, E, and K).
Concurrent use with stool softeners may increase absorption of mineral oil or produce more diarrhea.

Drug-Food:

Decreases absorption of fat-soluble vitamins (A, D, E, and K).

Availability ⬆ ⬇

(Generic available)

Liquid: 30-mL, 180-mL, pint, and gallon containers^OTC;
Jelly: 180-mL container^OTC;
Emulsion: 480-mL containers^OTC;
In combination with: magnesium hydroxide (Haley’s M-O) and glycerin^OTC. See Appendix [not included in this PDA edition].

Route/Dosage ⬆ ⬇

PO (Adults and Children >12 yr): 5–45 mL; Kondremul-30–75 mL.
PO (Children 6–12 yr): 5–15; Kondremul — 10–25 mL.
Rect (Adults and Children >12 yr): 60–150 mL as a single dose.
Rect (Children 2–11 yr): 30–60 mL as a single dose.

US Brand Names ⬆ ⬇

Fleet Mineral Oil, Kondremul Plain, Milkinol

Action ⬆ ⬇

Coats surface of stool and intestine with lubricant film to allow passage of stool through intestine.
Improves water retention of stool.
Therapeutic Effects:
Softening of fecal mass and subsequent passage.

Classifications ⬆ ⬇

Therapeutic Classification: laxatives
Pharmacologic Classification: lubricant laxatives

Pharmacokinetics ⬆ ⬇

Absorption: Minimally absorbed following oral administration.
Distribution: Distributes locally into the intestinal mucosa.
Metabolism/Excretion: Action is primarily local; unabsorbed mineral oil is passed with fecal mass.
Half-life: Not applicable.

Canadian Brand Names ⬆ ⬇

Kondremul, Lansoyl

Time/Action Profile ⬆ ⬇

(laxation)
ROUTE ONSET PEAK DURATION
PO 6–8 hr unknown unknown
Rect 2–15 min unknown unknown

Patient/Family Teaching ⬆ ⬇

Advise patients that laxatives should be used only for short-term therapy. Long-term therapy may interfere with absorption of nutrients and vitamins A, D, E, and K.
Advise patients not to take this medication within 2 hr of food or other medications.
Encourage patients to use other forms of bowel regulation, such as increasing bulk in the diet, increasing fluid intake, and increasing mobility. Normal bowel habits are variable and may vary from 3 times/day to 3 times/wk.
Instruct patients with cardiac disease to avoid straining during bowel movements (Valsalva maneuver).
Advise patients that large doses of mineral oil may cause leakage of mineral oil from the rectum; protection of clothing may be necessary. This may be prevented by reducing or dividing the dose or by administering in emulsified form.
Advise patients not to use laxatives when abdominal pain, nausea, vomiting, or fever is present.

Code ⬆

NDC Code^*
0132- C.B. Fleet Company, Inc.
0132-0301- FLEET 0132-0301-40- 133 mL in 1 BOTTLE, WITH APPLICATOR (0132-0301-40)
0363- Walgreen Co
0363-0831- Mineral Oil 0363-0831-43- 473 mL in 1 BOTTLE, PLASTIC (0363-0831-43)
0363- Walgreens
0363-0834- Mineral Oil 0363-0834-16- 473 mL in 1 BOTTLE, PLASTIC (0363-0834-16)
0395- Humco Holding Group, Inc.
0395-1673- Humco Mineral Oil Light 0395-1673-28- 3800 mL in 1 BOTTLE, PLASTIC (0395-1673-28)
0395- Humco Holding Group, Inc.
0395-1685- Humco Mineral Oil Heavy 0395-1685-28- 3800 mL in 1 BOTTLE, PLASTIC (0395-1685-28)
0869- Vi-Jon
0869-0831- oil 0869-0831-43- 473 mL in 1 BOTTLE, PLASTIC (0869-0831-43)
11673- TARGET Corporation
11673-034- Mineral oil 11673-034-16- 473 mL in 1 BOTTLE (11673-034-16)
11673- Target Corp
11673-831- Mineral Oil 11673-831-43- 473 mL in 1 BOTTLE, PLASTIC (11673-831-43)
11822- Rite Aid Corporation
11822-0603- Mineral Oil 11822-0603-2- 946 mL in 1 BOTTLE, PLASTIC (11822-0603-2)
11822- Rite Aid Corporation
11822-3340- Mineral Oil 11822-3340-6- 473 mL in 1 BOTTLE, GLASS (11822-3340-6)
11822- Rite Aid Corporation
11822-3601- Mineral Oil 11822-3601-6- 473 mL in 1 BOTTLE, PLASTIC (11822-3601-6)
15127- Select Brand Dist.
15127-334- Mineral oil 15127-334-16- 473 mL in 1 BOTTLE (15127-334-16)
15127- Select Brand
15127-831- Mineral Oil 15127-831-43- 473 mL in 1 BOTTLE, PLASTIC (15127-831-43)
21130- Safeway
21130-831- Mineral Oil 21130-831-43- 473 mL in 1 BOTTLE, PLASTIC (21130-831-43)
22431- Blue Cross Laboratories, Inc.
22431-135- Sesame Street Baby Oil 22431-135-01- 200 mL in 1 PACKAGE (22431-135-01)
30142- Kroger Co
30142-831- Mineral Oil 30142-831-43- 473 mL in 1 BOTTLE, PLASTIC (30142-831-43)
36800- TOP CARE (Topco Associates LLC)36800-334- Mineral Oil 36800-334-16- 473 mL in 1 BOTTLE, PLASTIC (36800-334-16)
36800- TopCo Associates
36800-931- Mineral Oil 36800-931-43- 473 mL in 1 BOTTLE, PLASTIC (36800-931-43)
37012- Shopko Stores Operating Co., LLC
37012-831- Mineral Oil 37012-831-43- 473 mL in 1 BOTTLE, PLASTIC (37012-831-43)
37205- Cardinal Health
37205-831- Mineral Oil 37205-831-43- 473 mL in 1 BOTTLE, PLASTIC (37205-831-43)
41163- Supervalu, Inc
41163-831- Mineral Oil 41163-831-43- 473 mL in 1 BOTTLE, PLASTIC (41163-831-43)
41190- WAKEFERN FOOD CORPORATION
41190-831- Mineral Oil 41190-831-43- 473 mL in 1 BOTTLE, PLASTIC (41190-831-43)
41250- Meijer Distribution Inc
41250-831- Mineral Oil 41250-831-43- 473 mL in 1 BOTTLE, PLASTIC (41250-831-43)
41520- Care One (American Sales Company)41520-334- Mineral Oil 41520-334-16- 473 mL in 1 BOTTLE, PLASTIC (41520-334-16)
41520- Foodhold U.S.A.
41520-877- Mineral Oil 41520-877-43- 473 mL in 1 BOTTLE, PLASTIC (41520-877-43)
46122- Amerisource Bergen
46122-103- Good Neighbor Pharmacy Hemorrhoidal 46122-103-46- 1 TUBE in 1 CARTON (46122-103-46) > 57 g in 1 TUBE
46122- AmerisourceBergen
46122-363- Good Neighbor Pharmacy Mineral Oil Laxative 46122-363-28- 1 BOTTLE in 1 CARTON (46122-363-28) > 133 mL in 1 BOTTLE
46122- AmerisourceBergen (Good Neighbor Pharmacy) 46122
46122-395- Mineral Oil 46122-395-16- 473 mL in 1 BOTTLE, PLASTIC (46122-395-16)
48433- Safecor Health, LLC
48433-202- MINERAL OIL 48433-202-30- 30 mL in 1 CUP, UNIT-DOSE (48433-202-30)
49035- EQUATE (Wal-Mart Stores, Inc.)49035-035- Mineral oil 49035-035-16- 473 mL in 1 BOTTLE (49035-035-16)
49348- McKesson
49348-185- Sunmark Mineral Oil Laxative
49348-185-20- 1 BOTTLE in 1 CARTON (49348-185-20) > 133 mL in 1 BOTTLE
49580- P and L Development, LLC
49580-0334- Mineral oil 49580-0334-6- 473 mL in 1 BOTTLE (49580-0334-6)
49738- SMART SENSE (Kmart)49738-334- Mineral oil 49738-334-16- 473 mL in 1 BOTTLE (49738-334-16)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-16- 100 mL in 1 BOTTLE (50346-005-16)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-17- 192 mL in 1 BOTTLE (50346-005-17)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-18- 200 mL in 1 BOTTLE (50346-005-18)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-19- 296 mL in 1 BOTTLE (50346-005-19)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-20- 355 mL in 1 BOTTLE (50346-005-20)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-21- 414 mL in 1 BOTTLE (50346-005-21)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-22- 474 mL in 1 BOTTLE (50346-005-22)
50346- Pan Aromas LLC
50346-005- Pan Aromas Baby 50346-005-23- 590 mL in 1 BOTTLE (50346-005-23)
50804- Geiss, Destin and Dunn, Inc
50804-831- Mineral Oil 50804-831-43- 473 mL in 1 BOTTLE, PLASTIC (50804-831-43)
53329- Medline Industries, Inc.
53329-013- Pure and Gentle 53329-013-11- 1 BOTTLE in 1 BOX (53329-013-11) > 133 mL in 1 BOTTLE
54162- GERITREX LLC
54162-175- Mineral oil 54162-175-05- 113 g in 1 BOTTLE, WITH APPLICATOR (54162-175-05)
54162- GERITREX LLC
54162-175- Mineral oil 54162-175-12- 113 g in 1 BOTTLE, WITH APPLICATOR (54162-175-12)
54162- GERITREX LLC
54162-185- Mineral oil Light, N.F 54162-185-16- 472 mL in 1 BOTTLE (54162-185-16)
54162- Geritrex LLC
54162-190- Mineral Oil 54162-190-16- 472 mL in 1 BOTTLE, PLASTIC (54162-190-16)
54799- OCuSOFT, Inc.
54799-917- retaine MGD 54799-917-30- 30 VIAL, SINGLE-DOSE in 1 CONTAINER (54799-917-30) >.4 mL in 1 VIAL, SINGLE-DOSE
55301- Your Military Exchanges
55301-831- Mineral Oil 55301-831-43- 473 mL in 1 BOTTLE, PLASTIC (55301-831-43)
55312- Western Family Foods, Inc.
55312-831- Mineral Oil 55312-831-43- 473 mL in 1 BOTTLE, PLASTIC (55312-831-43)
55315- Freds Inc
55315-334- Mineral Oil 55315-334-16- 473 mL in 1 BOTTLE, PLASTIC (55315-334-16)
55316- DZA Brands LLC
55316-831- Mineral Oil 55316-831-43- 473 mL in 1 BOTTLE, PLASTIC (55316-831-43)
55319- Family Dollar (FAMILY WELLNESS)55319-634- Mineral Oil 55319-634-16- 473 mL in 1 BOTTLE, PLASTIC (55319-634-16)
55910- DOLGENCORP, LLC
55910-831- Mineral Oil 55910-831-43- 473 mL in 1 BOTTLE, PLASTIC (55910-831-43)
56062- Publix Supermarkets, Inc.
56062-334- Mineral Oil 56062-334-16- 473 mL in 1 BOTTLE, PLASTIC (56062-334-16)
60899- AMAROS CO., LTD.
60899-050- Seaweed Cleansing 60899-050-01- 150 mL in 1 CARTON (60899-050-01)
61715- Preferred Plus (Kinray)61715-163- Mineral Oil 61715-163-16- 473 mL in 1 BOTTLE, PLASTIC (61715-163-16)
62011- McKesson
62011-0270- HealthMart Mineral Oil Single Laxative
62011-0270-1- 1 BOTTLE in 1 CARTON (62011-0270-1) > 133 mL in 1 BOTTLE
63736- Insight Pharmaceuticals LLC
63736-042- Kondremul 63736-042-16- 480 mL in 1 BOTTLE (63736-042-16)
63868- Chain Drug Marketing Association
63868-201- Quality Choice Hemorrhoidal 63868-201-02- 1 TUBE in 1 CARTON (63868-201-02) > 57 g in 1 TUBE
63868- QUALITY CHOICE (Chain Drug Marketing Association)63868-938- Mineral oil 63868-938-16- 473 mL in 1 BOTTLE (63868-938-16)
63941- Best Choice (Valu Merchandisers Company)63941-334- Mineral oil 63941-334-16- 473 mL in 1 BOTTLE (63941-334-16)
65923- United Exchange Corp
65923-003- Family Care Hemorrhoidal 65923-003-20- 1 TUBE in 1 CARTON (65923-003-20) > 20 g in 1 TUBE
67234- Natureplex LLC
67234-019- Enema Mineral Oil 67234-019-01- 1 BOTTLE, WITH APPLICATOR in 1 CARTON (67234-019-01) > 133 mL in 1 BOTTLE, WITH APPLICATOR
68788- Preferred Pharmaceuticals Inc.
68788-7055- Mineral Oil 68788-7055-4- 472 mL in 1 BOTTLE, PLASTIC (68788-7055-4)
69256- Harris Teeter, LLC
69256-334- Mineral oil 69256-334-16- 473 mL in 1 BOTTLE (69256-334-16)
70000- Cardinal Health
70000-0109- Leader Ready to Use Mineral Oil Laxative
70000-0109-1- 1 BOTTLE in 1 CARTON (70000-0109-1) > 133 mL in 1 BOTTLE
70000- Cardinal Health
70000-0448- LEADER Mineral Oil 70000-0448-1- 473 mL in 1 BOTTLE, PLASTIC (70000-0448-1)
70818- C3 Co., Ltd.
70818-010- isLeaf Shine Smooth Lip Glaze Soft Pink 70818-010-01- 2.5 mL in 1 APPLICATOR (70818-010-01)
70818- C3 Co., Ltd.
70818-011- isLeaf Shine Smooth Lip Glaze Red 70818-011-01- 2.5 mL in 1 APPLICATOR (70818-011-01)
70818- C3 Co., Ltd.
70818-012- isLeaf Shine Smooth Lip Glaze Orange 70818-012-01- 2.5 mL in 1 APPLICATOR (70818-012-01)
70818- C3 Co., Ltd.
70818-013- isLeaf Shine Smooth Lip Glaze Pearl Red 70818-013-01- 2.5 mL in 1 APPLICATOR (70818-013-01)