Contraindicated in:
Use Cautiously in:
CV: edema of the hands and feet.
Endo: hyperglycemia, hypothyroidism, insulin resistance.
GI: PANCREATITIS.
Local: pain at injection site, local lipoatrophy or lipodystrophy with subcutaneous use.
MS: arthralgia.
Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA).
Drug-Drug:
Adult Growth Hormone Deficiency
Pediatric Growth Hormone Deficiency
Short Stature Associated with Noonan or Turner Syndrome
Short Stature Born Small for Gestational Age
Absorption: Well absorbed.
Distribution: Localize to highly perfused organs (liver, kidneys).
Metabolism/Excretion: Broken down in renal cells to amino acids that are recirculated; some liver metabolism.
Half-life: Subcut 3.8 hr.