- PO (Adults): 4 g 1–2 times daily (initially, may be increased as needed/tolerated up to 24 g/day in 6 divided doses).
- PO (Children): 240 mg/kg/day in 2–3 divided doses (not >8 g/day).
Unlabeled Use:
Contraindicated in:
Use Cautiously in:
Exercise Extreme Caution in:
Derm: irritation, rashes.
EENT: irritation of the tongue.
F and E: hyperchloremic acidosis.
GI: abdominal discomfort, constipation, nausea, fecal impaction, flatulence, hemorrhoids, perianal irritation, steatorrhea, vomiting.
Metab: vitamin A, D, and K deficiency.
Drug-Drug:
(Generic available)
Prevalite, Questran, Questran Light
Therapeutic Classification: lipid-lowering agents
Pharmacologic Classification: bile acid sequestrants
Absorption: Action takes place in the GI tract. No absorption occurs.
Distribution: No distribution.
Metabolism/Excretion: After binding bile acids, insoluble complex is eliminated in the feces.
Half-life: Unknown.
NDC Code*