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Indications

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS


Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: hypotension

GI: abdominal cramps, nausea, vomiting

Neuro: dizziness, drowsiness, headache

Interactions

Natural-Drug Products:

Natural-Natural Products:

Availability

Route/Dosage

US Brand Names

pineal hormone, N-acetyl-5–methoxtryptamine

Action

  • Melatonin is a hormone secreted from the pineal gland in a 24-hour circadian rhythm, regulating the normal sleep/wake cycle. As a supplement, melatonin has both phase-shifting and sleep-promoting properties. In addition to promoting sleep, physiologic roles of melatonin include regulation of the secretion of growth hormone and gonadotropic hormones. It also possesses antioxidant activity.
Therapeutic effects:
  • Improved sleep pattern.

Classifications

Therapeutic Classification: sedative/hypnotics

Pharmacokinetics

Absorption: Unknown

Distribution: Unknown

Metabolism/Excretion: Unknown

Half-Life: Unknown

Time/Action Profile

ONSETPEAKDURATION
POunknownunknownunknown

Patient/Family Teaching

Pronunciation

mel-uh-TOH-nin

Code

NDC Code