Acetaminophen Overdose
- PO (Adults and Children ): 140 mg/kg initially, followed by 70 mg/kg every 4 hr for 17 additional doses.
- IV (Adults and Children ): Loading dose: 150 mg/kg (maximum: 15 g) over 60 min initially, followed by First maintenance dose: 50 mg/kg (maximum: 5 g) over 4 hr. Second maintenance dose: 100 mg/kg (maximum: 10 g) over 16 hr.
Mucolytic
- Inhaln (Adults and Children 1–12 yr): Nebulization via face mask: 3–5 mL of 20% solution or 6–10 mL of the 10% solution 3–4 times daily; Nebulization via tent or croupette: volume of 10–20% solution required to maintain heavy mist; Direct instillation: 1–2 mL of 10–20% solution every 1–4 hr; Intratracheal instillation via tracheostomy: 1–2 mL of 10–20% solution every 1–4 hr (up to 2–5 mL of 20% solution via tracheal catheter into particular segments of the bronchopulmonary tree).
- Inhaln (Infants ): Nebulization: 1–2 mL of 20% solution or 2–4 mL of 10% solution 3–4 times daily.
Prevention of Radiocontrast-Induced Renal Impairment
- PO (Adults ): 600 mg twice daily for 2 days, beginning the day before the procedure.
