- PO (Adults): 1.25–2.5 mg initially; if headache returns, dose may be repeated after 2 hr (not to exceed 10 mg/24 hr); Concurrent use of cimetidine: Single dose not to exceed 2.5 mg (not to exceed 5 mg/24 hr).
Hepatic Impairment
- PO (Adults): Moderate to severe hepatic impairment (oral tablets only): 1.25 mg initially; if headache returns, dose may be repeated after 2 hr (not to exceed 5 mg/24 hr).
- Intranasal (Adults and Children
12 yr): Single 2.5 mg initially (maximum single dose = 5 mg); may be repeated after 2 hr (not to exceed 10 mg/24 hr); Concurrent use of cimetidine: Single dose not to exceed 2.5 mg (not to exceed 5 mg/24 hr).