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Indications

REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Derm: pruritis.

GI: liver function tests, abnormal mouth sensations, nausea, vomiting.

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Mycelex

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antifungals (oral, nonabsorbed)

Pharmacokinetics

Absorption: Minimal systemic absorption.

Distribution: Inhibitory concentrations remain in saliva for up to 3 hr after troche dissolves.

Metabolism/Excretion: Metabolized by liver; <1% excreted unchanged in urine.

Half-life: 24 hr.

Time/Action Profile

ROUTEONSETPEAKDURATION
POunknownunknownup to 3 hr

Patient/Family Teaching

Pronunciation

kloe-TRIM-a-zole

Code

NDC Code*