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Indications ⬇

REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

Derm: allergic contact dermatitis, atrophy, burning, dryness, edema, folliculitis, hypersensitivity reactions, hypertrichosis, hypopigmentation, irritation, maceration, miliaria, perioral dermatitis, secondary infection, striae

Misc: adrenal suppression (use of occlusive dressings, long-term therapy)

Interactions ⬆ ⬇

Drug-drug:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Clobex, Impeklo, Impoyz, Olux, Olux-E, Temovate, Temovate E

Action ⬆ ⬇

  • Suppresses normal immune response and inflammation.
Therapeutic effects:
  • Suppression of dermatologic inflammation and immune processes.

Classifications ⬆ ⬇

Therapeutic Classification: corticosteroids

Pharmacologic Classification: corticosteroids

Pharmacokinetics ⬆ ⬇

Absorption: Minimal. Prolonged use on large surface areas or large amounts applied or use of occlusive dressings may increase systemic absorption.

Distribution: Remains primarily at site of action.

Metabolism/Excretion: Usually metabolized in skin; may be modified to resist local metabolism and have a prolonged local effect.

Half-Life: Unknown.

Canadian Brand Names ⬆ ⬇

Dermovate

Time/Action Profile ⬆ ⬇

(response depends on condition being treated)

ROUTEONSETPEAKDURATION
Topicalmin–hrshrs–dayshrs–days

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

kloe-BAY-ta-sol

Code ⬆

NDC Code