CreamTreatment of a variety of cutaneous fungal infections, including cutaneous candidiasis, tinea pedis (athlete’s foot), tinea cruris (jock itch), tinea corporis (ringworm), and tinea versicolor.
FoamTreatment of interdigital tinea pedis
Contraind./Precautions⬆⬇
Contraindicated in:
Hypersensitivity to active ingredients, additives, preservatives, or bases.
Use Cautiously in:
Nail and scalp infections (may require additional systemic therapy);
OB: Safety not established.
Adv. Reactions/Side Effects⬆⬇
Local: burning, itching, local hypersensitivity reactions, redness, stinging
(Adults and Children ): Apply once daily in patients with tinea pedis (for 1 mo), tinea cruris (for 2 wk), tinea corporis (for 2 wk), and tinea versicolor (for 2 wk). Apply twice daily in patients with cutaneous candidiasis (for 2 wk).
US Brand Names⬆⬇
Ecoza
Action⬆⬇
Affects the permeability of the fungal cell wall, allowing leakage of cellular contents.
Therapeutic effects:
Decrease in symptoms of fungal infection.
Classifications⬆⬇
Therapeutic Classification: antifungals (topical)
Pharmacokinetics⬆⬇
Absorption: Absorption through intact skin is minimal.
Distribution: Distribution after topical administration is primarily local.
Metabolism/Excretion: Metabolism in the liver and <1% excreted in the urine and feces.
Half-Life: Not applicable.
Time/Action Profile⬆⬇
ROUTE
ONSET
PEAK
DURATION
Top
unknown
unknown
unknown
Patient/Family Teaching⬆⬇
Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Emphasize the importance of avoiding the eyes.
Caution patient that some products may stain fabric, skin, or hair. Check label information. Fabrics stained from cream can usually be cleaned by handwashing with soap and warm water.
Patients with athlete’s foot should be taught to wear well-fitting, ventilated shoes, to wash affected areas thoroughly, and to change shoes and socks at least once a day.
Advise patient to report increased skin irritation or lack of response to therapy to health care professional.
Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Advise patient that early relief of symptoms may be seen in 2–3 days. For Candida, tinea cruris, tinea corporis, and tinea versicolor, 2 wk are needed, and for tinea pedis, therapeutic response may take 4 wk. Recurrent fungal infections may be a sign of systemic illness.
Pronunciation⬆⬇
ee-KON-a-zole
Code⬆
NDC Code
0168- E. Fougera and Co. a division of Fougera Pharmaceuticals Inc.
