Contraindicated in:
Use Cautiously in:
CV: palpitations, QT interval prolongation, TORSADES DE POINTES.
EENT: tinnitus.
GI: abdominal pain, constipation, dry mouth, nausea, vomiting.
GU: acute renal failure.
Neuro: dizziness, headache.
Drug-Drug:
Drug-Natural Products:
Drug-Food:
(Generic available)
Aspruzyo Sprinkle, Ranexa
Absorption: Highly variable.
Distribution: Unknown.
Metabolism/Excretion: Metabolized by the liver primarily by the CYP3A isoenzyme and to a lesser extent by the CYP2D6 isoenzyme; <5% excreted unchanged in urine and feces.
Half-life: 7 hr.
NDC Code*