Alkalinization of Urine
- PO (Adults): 48 mEq (4 g) initially, then 12–24 mEq (1–2 g) every 4 hr (up to 48 mEq every 4 hr) or 1 tsp of powder every 4 hr as needed.
- PO (Children): 1–10 mEq/kg/day (84–840 mg/kg/day) in divided doses.
- IV (Adults and Children): 2–5 mEq/kg as a 4–8-hr infusion.
Antacid
- PO (Adults): Tablets/powder: 325 mg–2 g 1–4 times daily or ½ tsp every 2 hr as needed. Effervescent powder: 3.9–10 g in water after meals; patients >60 yr should receive 1.9–3.9 g after meals.
Systemic Alkalinization/Cardiac Arrest
- IV (Adults and Children and Infants): Cardiac arrest/urgent situations: 1 mEq/kg; may repeat 0.5 mEq/kg every 10 min. Less urgent situations: 2–5 mEq/kg as a 4–8-hr infusion.
- PO (Adults): 0.5–2 mEq/kg/day in 4–5 divided doses.
- PO (Children): 2–3 mEq/kg/day in 3–4 divided doses.