EENT: epistaxis, nasal burning, nasal irritation, nasopharyngeal fungal infection, otitis media, pharyngitis, rhinitis, sinusitis, sneezing.
Endo: adrenal suppression (high-dose, long-term therapy only).
GI: vomiting.
Neuro: headache.
Resp: cough.
Therapeutic Classification: corticosteroids
Absorption: Action of all agents is primarily local after nasal use.
Distribution: Crosses the placenta and enters breast milk in small amounts.
Metabolism/Excretion: Rapidly and extensively metabolized by the liver; 40% excreted in urine, 60% in feces.
Half-life: 3–5.4 hr.
(improvement in symptoms)
12 yr): 2 sprays in each nostril once daily; not to be used in children for longer than 2 mo.