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Indications ⬇

BEERS REMS

Unlabeled Use:

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

Derm: sweating

Endo: SIADH

F and E: hyponatremia

GI: diarrhea, nausea, abdominal pain, constipation, dry mouth, indigestion

GU: ↓libido, delayed/absent orgasm, ejaculatory delay/failure, erectile dysfunction

Hemat: BLEEDING

Metab: ↑appetite

Neuro: insomnia, dizziness, drowsiness, fatigue, NEUROLEPTIC MALIGNANT SYNDROME, SUICIDAL THOUGHTS

Misc: SEROTONIN SYNDROME

Interactions ⬆ ⬇

Drug-drug:

Drug-Natural Products:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

Major Depressive Disorder

Hepatic Impairment

Generalized Anxiety Disorder

Hepatic Impairment

US Brand Names ⬆ ⬇

Lexapro

Action ⬆ ⬇

  • Selectively inhibits the reuptake of serotonin in the CNS.
Therapeutic effects:
  • Antidepressant action.

Classifications ⬆ ⬇

Therapeutic Classification: antidepressants

Pharmacologic Classification: selective serotonin reuptake inhibitors ssris

Pharmacokinetics ⬆ ⬇

Absorption: 80% absorbed following oral administration.

Distribution: Enters breast milk.

Metabolism/Excretion: Mostly metabolized by the liver, primarily by the CYP3A4 and CYP2C19 isoenzymes; 7% excreted unchanged by kidneys.

Half-Life: 27–32 hr (↑ in elderly and hepatic impairment).

Canadian Brand Names ⬆ ⬇

Cipralex

Time/Action Profile ⬆ ⬇

(antidepressant effect)

ROUTEONSETPEAKDURATION
POwithin 1–4 wkunknownunknown

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

ess-sit-AL-o-pram

Pill Image

escitalopramoxalate_319-131.jpg

Code ⬆

NDC Code