⬇ ⬇ ⬆ ⬇Contraindicated in:
Use Cautiously in:
⬆ ⬇Resp: cough, pharyngitis
GI: anorexia, nausea, vomiting
F and E: metabolic acidosis
GU: kidney stones
Derm: STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS, oligohydrosis (↑ in children), rash
Neuro: abnormal gait, hyperasthesia, incoordination, tremor
Misc: DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (DRESS)
⬆ ⬇Drug-drug:
⬆ ⬇ ⬆ ⬇ ⬆ ⬇ ⬆ ⬇ ⬆ ⬇ ⬆ ⬇Absorption: Well absorbed following oral administration.
Distribution: Binds extensively to red blood cells.
Protein Binding: 40%.
Half-Life: 63 hr (plasma).
⬆ ⬇| ROUTE | ONSET | PEAK | DURATION |
|---|---|---|---|
| PO | unknown | 2–6 hr | 24 hr |
‡Requires 2 wk of dosing to achieve steady-state blood levels.
⬆ ⬇ ⬆ ⬇ ⬆NDC Code
