Contraindicated in:
Use Cautiously in:
CNS: abnormal thinking, behavior changes, hangover, dizziness, drowsiness, hallucinations, lethargy, paradoxic excitation, sleep — driving.
Derm: rash.
EENT: blurred vision.
GI: constipation, diarrhea, nausea, vomiting.
Misc: physical dependence, psychological dependence, tolerance.
Drug-Drug:
Drug-Natural Products:
(Generic available)
Absorption: Well absorbed after oral administration.
Distribution: Widely distributed; crosses blood-brain barrier. Probably crosses the placenta and enters breast milk. Accumulation of drug occurs with chronic dosing.
Protein Binding: 96%.
Metabolism/Excretion: Metabolized by the liver.
Half-life: 10–20 hr.
NDC Code*