Contraindicated in:

• None.

Use Cautiously in:

• Compromised respiratory function/acute respiratory disease (increased risk of infusion reactions);
• Severe genetic mutations (↑ risk of serious adverse reactions);
• Patients at risk for fluid overload, acute respiratory disorder, cardiac or respiratory illness (↑ risk of compromised cardiac or respiratory function);
• OB: Use during pregnancy only if potential maternal benefit outweighs potential fetal risk;
• Lactation: Use while breastfeeding only if potential maternal benefit outweighs risk to infant;
• Pedi: Children <16 mo (safety not established).