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Indications

BEERS REMS

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: edema, THROMBOEMBOLISM.

Derm: alopecia.

Endo: asymptomatic adrenal suppression (chronic therapy).

GI: GI irritation.

GU: vaginal bleeding.

MS: carpal tunnel syndrome.

Interactions

Drug-Drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Megace

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antineoplastics, hormones

Pharmacologic Classification: progestins

Pharmacokinetics

Absorption: Well absorbed from the GI tract.

Distribution: Unknown.

Protein Binding: ge.gif90%.

Metabolism/Excretion: Completely metabolized by the liver.

Half-life: 38 hr (range 13–104 hr).

Time/Action Profile

(antineoplastic activity)

ROUTEONSETPEAKDURATION
POwk–mos2 mounknown

Patient/Family Teaching

Pronunciation

me-JESS-trole

Code

NDC Code*