astragalus

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Indications ⬇

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS

Common cold.
Allergic rhinitis.

Contraind./Precautions ⬆ ⬇

Contraindicated in:

No known contraindications.

Use Cautiously in:

Pregnancy and lactation;
May exacerbate autoimmune diseases.

Adv. Reactions/Side Effects ⬆ ⬇

GI: nausea

Misc: immunosuppression (with doses >28 grams/day)

Interactions ⬆ ⬇

Natural-Drug Products:

May reduce the effects ofimmunosuppressants.
May reduce excretion and increase levels of lithium.

Natural-Natural Products:

None.

Availability ⬆ ⬇

Capsules: 470 mg

Route/Dosage ⬆ ⬇

PO (Adults ): Allergic rhinitis:160 mg of astragalus root extract twice daily. Common cold prevention:4–7 g per day.

US Brand Names ⬆ ⬇

Astragali Membranaceus, Membranous Milk Vetch

Action ⬆ ⬇

Astragalus has antioxidant effects. It inhibits free radical production, increases superoxide dismutase, and decreases lipid peroxidation. Astragalus potentiates effects of interferon, increases antibody levels of IgA and IgG in nasal secretions, and increases interleukin-2 (IL-2) levels.

Therapeutic effects:

Improved immune response.

Classifications ⬆ ⬇

Therapeutic Classification: allergy, cold and cough remedies

Pharmacokinetics ⬆ ⬇

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

ROUTE	ONSET	PEAK	DURATION
unknown	unknown	unknown	unknown

Patient/Family Teaching ⬆ ⬇

Discuss purpose of astragalus with patient.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Pronunciation ⬆

a-STRAG-uh-luh-s