RSV Infection
- Inhaln (Infants and Young Children): 300 mL of 20 mg/mL solution delivered via mist for 12–18 hr/day.
Chronic Hepatitis C
Viral Genotype 1 or 4- PO (Adults
75 kg): 600 mg twice daily for 48 wk. - PO (Adults <75 kg): 500 mg twice daily for 48 wk.
- PO (Children 5 yr and 75 kg): 600 mg in the morning, then 600 mg in the evening for 48 wk.
- PO (Children 5 yr and 60–74 kg): 400 mg in the morning, then 600 mg in the evening for 48 wk.
- PO (Children 5 yr and 47–59 kg): 400 mg in the morning, then 400 mg in the evening for 48 wk.
- PO (Children 5 yr and 34–46 kg): 200 mg in the morning, then 400 mg in the evening for 48 wk.
- PO (Children 5 yr and 23–33 kg): 200 mg in the morning, then 200 mg in the evening for 48 wk.
Renal Impairment
- PO (Adults): CCr 30–50 mL/min — 200 mg/day alternating with 400 mg/day every other day for 48 wk; CCr <30 mL/min or Hemodialysis — 200 mg once daily for 48 wk. Viral Genotype 2 or 3
- PO (Adults): 400 mg twice daily for 24 wk.
- PO (Children 5 yr and 75 kg): 600 mg in the morning, then 600 mg in the evening for 24 wk.
- PO (Children 5 yr and 60–74 kg): 400 mg in the morning, then 600 mg in the evening for 24 wk.
- PO (Children 5 yr and 47–59 kg): 400 mg in the morning, then 400 mg in the evening for 24 wk.
- PO (Children 5 yr and 34–46 kg): 200 mg in the morning, then 400 mg in the evening for 24 wk.
- PO (Children 5 yr and 23–33 kg): 200 mg in the morning, then 200 mg in the evening for 24 wk.
Renal Impairment
- PO (Adults): CCr 30–50 mL/min — 200 mg/day alternating with 400 mg/day every other day for 24 wk; CCr <30 mL/min or Hemodialysis — 200 mg once daily for 24 wk.