Contraindicated in:
Use Cautiously in:
Exercise Extreme Caution in:
CNS: anxiety, depression, dizziness, sedation, weakness, dyskinesia, hallucinations, nervousness.
EENT: blurred vision, pharyngitis, rhinitis.
CV: hypotension, bradycardia.
GI: abdominal pain, diarrhea, dry mouth, dyspepsia, constipation, hepatocellular injury, ↑ liver enzymes, vomiting.
GU: urinary frequency.
Derm: rash, skin ulcers, sweating.
MS: back pain, myasthenia, paresthesia.
Misc: fever, speech disorder.
Drug-Drug:
(Generic available)
Tablets are not interchangeable with capsules
Therapeutic Classification: antispasticity agents (centrally acting)
Pharmacologic Classification: adrenergics
Absorption: Completely absorbed after oral administration but rapidly metabolized, resulting in 40% bioavailability.
Distribution: Widely distributed.
Metabolism/Excretion: 95% metabolized by the liver.
Half-life: 2.5 hr.
NDC Code*