Treatment of Ulcerative Colitis
- PO (Adults): 1.6 g (two 800-mg tablets) 3 times daily for 6 wk; Delzicol: 800 mg (two 400-mg capsules) 3 times daily for 6 wk; Lialda: 2.4–4.8 g (two to four 1.2-g tablets) once daily for up to 8 wk; Pentasa: 1 g (four 250-mg capsules or two 500-mg capsules) 4 times daily for up to 8 wk.
- Rect (Adults): Rowasa: 4-g enema (60 mL) at bedtime, retained for 8 hr for 3–6 wk.
- PO (Children
12 yr and 54–90 kg): Delzicol: 27–44 mg/kg/day in 2 divided doses (max dose = 2.4 g/day) for 6 wk. - PO (Children 12 yr and 33–53 kg): Delzicol: 37–61 mg/kg/day in 2 divided doses (max dose = 2 g/day) for 6 wk.
- PO (Children 12 yr and 17–32 kg): Delzicol: 36–71 mg/kg/day in 2 divided doses (max dose = 1.2 g/day) for 6 wk.
- PO (Children >50 kg): Lialda: 4.8 g (four 1.2-g tablets) once daily for 8 wk, then 2.4 g (two 1.2-g tablets) once daily.
- PO (Children 36–50 kg): Lialda: 3.6 g (three 1.2-g tablets) once daily for 8 wk, then 2.4 g (two 1.2-g tablets) once daily.
- PO (Children 24–35 kg): Lialda: 2.4 g (two 1.2-g tablets) once daily for 8 wk, then 1.2 g once daily.
Maintenance of Remission of Ulcerative Colitis
- PO (Adults): Apriso: 1.5 g (four 375-mg capsules) once daily in the morning; Delzicol: 800 mg (two 400-mg capsules) 2 times daily; Lialda: 2.4 g (two 1.2-g tablets) once daily; Pentasa: 1 g (four 250-mg capsules or two 500-mg capsules) 4 times daily.
Treatment of Ulcerative Proctosigmoiditis
- Rect (Adults): Rowasa: 4-g enema (60 mL) at bedtime, retained for 8 hr (treatment duration = 3–6 wk).
Treatment of Ulcerative Proctitis
- Rect (Adults): Rowasa: 4-g enema (60 mL) at bedtime, retained for 8 hr (treatment duration = 3–6 wk); Canasa: Insert a 1-g suppository at bedtime, retain for at least 1–3 hr (treatment duration = 3–6 wk).