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Indications

REMS


Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

EENT: nasal burning, rebound nasal congestion (if used for >3 days), sneezing

Interactions

Drug-drug:

Availability

Route/Dosage

US Brand Names

Afrin, Vicks Sinex

Action

  • Stimulates alpha-1 adrenergic receptors in the arterioles of the nasal mucosa, leading to vasoconstriction.
Therapeutic effects:
  • Reduction of nasal congestion and sinus congestion/pressure.

Classifications

Therapeutic Classification: decongestants/vasoconstrictors

Pharmacologic Classification: adrenergics

Pharmacokinetics

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile

(reduction of nasal congestion)

ROUTEONSETPEAKDURATION
Intranasalwithin 10 minunknownup to 12 hr

Patient/Family Teaching

Pronunciation

oxs-ee-met-AZ-oh-leen