Viagra:
Revatio and Liqrev:
Contraindicated in:
Use Cautiously in:
CV: hypotension, MI, SUDDEN DEATH, vaso-occlusive crises.
Derm: flushing, rash.
EENT: epistaxis, hearing loss, nasal congestion, vision loss.
GI: dyspepsia, diarrhea.
GU: priapism, urinary tract infection.
MS: myalgia.
Neuro: headache, dizziness, insomnia, paresthesia.
Drug-Drug:
(Generic available)
Erectile Dysfunction
Hepatic Impairment
Pulmonary Arterial Hypertension
IV therapy is indicated for patients unable to take PO therapyTherapeutic Classification:erectile dysfunction agents, vasodilators
Pharmacologic Classification: phosphodiesterase type 5 inhibitors
Absorption: Rapidly absorbed (41%) after oral administration; IV administration results in complete bioavailability.
Distribution: Widely distributed to tissues; negligible amount in semen.
Protein Binding: 96%.
Metabolism/Excretion: Primarily metabolized by the liver via the CYP3A4 isoenzyme; one metabolite is active and accounts for 20% or more of drug effect. Metabolites excreted mostly (80%) in feces; 13% excreted in urine.
Half-life: 4 hr (for sildenafil and active metabolite).
NDC Code*