Treatment of a variety of cutaneous fungal infections, including tinea pedis (athlete’s foot), tinea cruris (jock itch), tinea corporis (ringworm).
Contraind./Precautions⬆⬇
Contraindicated in:
Hypersensitivity to active ingredients, additives, preservatives, or bases;
Some products contain alcohol or bisulfites and should be avoided in patients with known intolerance.
Use Cautiously in:
Nail and scalp infections (may require additional systemic therapy);
OB: Safety not established.
Adv. Reactions/Side Effects⬆⬇
Local: burning, itching, local hypersensitivity reactions, redness, stinging
Interactions⬆⬇
Drug-drug:
Not known.
Availability⬆⬇
(Generic available)
Cream: 2%Rx, OTC
Lotion powder: 2%OTC
Ointment: 2%OTC
Powder: 2%OTC
Solution: 2%OTC
Spray liquid: 2%OTC
Spray powder: 2%OTC
Tincture: 2%OTC
In combination with: zinc oxide (Vusion)RxAppendix [not included in this PDA edition].
Route/Dosage⬆⬇
(Adults and Children > 2 yr): Apply twice daily. Treat patients with tinea cruris for 2 wk and patients with tinea pedis or tinea corporis for 4 wk.
US Brand Names⬆⬇
Fungoid, Lotrimin AF, Micatin, Zeasorb-AF
Action⬆⬇
Affects the synthesis of the fungal cell wall, allowing leakage of cellular contents.
Therapeutic effects:
Decrease in symptoms of fungal infection.
Classifications⬆⬇
Therapeutic Classification: antifungals (topical)
Pharmacokinetics⬆⬇
Absorption: Absorption through intact skin is minimal.
Distribution: Distribution after topical administration is primarily local.
Metabolism/Excretion: Systemic metabolism and excretion not known following local application.
Half-Life: Not applicable.
Canadian Brand Names⬆⬇
Micozole
Time/Action Profile⬆⬇
ROUTE
ONSET
PEAK
DURATION
Top
unknown
unknown
unknown
Patient/Family Teaching⬆⬇
Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Emphasize the importance of avoiding the eyes.
Caution patient that some products may stain fabric, skin, or hair. Check label information. Fabrics stained from cream or lotion can usually be cleaned by handwashing with soap and warm water; stains from ointments can usually be removed with standard cleaning fluids.
Patients with athlete’s foot should be taught to wear well-fitting, ventilated shoes, to wash affected areas thoroughly, and to change shoes and socks at least once a day.
Advise patient to report increased skin irritation or lack of response to therapy to health care professional.