Unlabeled Use:
Contraindicated in:
Use Cautiously in:
CV: hypotension, QT interval prolongation, tachycardia, TORSADES DE POINTES, ventricular arrhythmias.
Derm: diaphoresis, photosensitivity, rash.
EENT: blurred vision, dry eyes.
Endo: amenorrhea, galactorrhea, gynecomastia.
GI: constipation, dry mouth, anorexia, hepatitis, ileus.
GU: impotence, urinary retention.
Hemat: AGRANULOCYTOSIS, anemia, leukopenia, neutropenia.
Metab: weight gain.
Neuro: extrapyramidal reactions, confusion, drowsiness, restlessness, SEIZURES, tardive dyskinesia.
Resp: respiratory depression.
Misc: hypersensitivity reactions, NEUROLEPTIC MALIGNANT SYNDROME.
Drug-Drug:
Drug-Natural Products:
(Generic available)
Haloperidol
Haloperidol Decanoate
Haldol, Haldol Decanoate
Absorption: Well absorbed following PO/IM administration. Decanoate salt is slowly absorbed and has a long duration of action.
Distribution: Concentrates in liver.
Protein Binding: 92%.
Metabolism/Excretion: Mostly metabolized by the liver.
Half-life: 2124 hr.
(antipsychotic activity)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | 2 hr | 26 hr | 812 hr |
IM | 2030 min | 3045 min | 48 hr |
IM (decanoate) | 39 days | unknown | 1 mo |
NDC Code*