In combination with: hydrocodone (Obredon, Xtrelus); hydrocodone and pseudoephedrine (Hycofenix); analgesics/antipyretics, antihistamines, decongestants, and cough suppressants. See Appendix [not included in this PDA edition].
Route/Dosage⬆⬇
PO (Adults ): 200–400 mg every 4 hr or 600–1200 mg every 12 hr as extended-release product (not to exceed 2400 mg/day).
PO (Children 6–12 yr): 100–200 mg every 4 hr or 600 mg every 12 hr as extended-release product (not to exceed 1200 mg/day).
PO (Children 4–6 yr): 50–100 mg every 4 hr (not to exceed 600 mg/day).
Reduces viscosity of tenacious secretions by increasing respiratory tract fluid.
Therapeutic effects:
Mobilization and subsequent expectoration of mucus.
Classifications⬆⬇
Therapeutic Classification: allergy, cold and cough remedies, expectorant
Pharmacokinetics⬆⬇
Absorption: Well absorbed after oral administration.
Distribution: Unknown.
Metabolism/Excretion: Renally excreted as metabolites.
Half-Life: Unknown.
Canadian Brand Names⬆⬇
Balminil Expectorant, Benylin Chest Congestion Extra Strength, Bronchophan Expectorant, Chest Congestion, Cough Syrup Expectorant, Expectorant Syrup, Jack & Jill Expectorant, Vicks Chest Congestion Relief, Vicks Dayquil Mucus Control
Time/Action Profile⬆⬇
(expectorant action)
ROUTE
ONSET
PEAK
DURATION
PO
30 min
unknown
4–6 hr
PO-ER
unknown
unknown
12 hr
Patient/Family Teaching⬆⬇
Instruct patient to cough effectively. Patient should sit upright and take several deep breaths before attempting to cough.
Caution parents to avoid OTC cough and cold products while breast feeding or administering to children <4 yrs.
Advise patient that guaifenesin is a drug with known abuse potential. Protect it from theft, and never give to anyone other than the individual for whom it was recommended. Store out of sight and reach of children, and in a location not accessible by others.
Inform patient that drug may occasionally cause dizziness. Avoid driving or other activities requiring alertness until response to drug is known.
Advise patient to limit talking, stop smoking, maintain moisture in environmental air, and take some sugarless gum or hard candy to help alleviate the discomfort caused by a chronic nonproductive cough.
Instruct patient to contact health care professional if cough persists longer than 1 wk or is accompanied by fever, rash, or persistent headache or sore throat.
Advise patient to notify health care professional if pregnancy is planned or suspected, or if breastfeeding.
Pronunciation⬆⬇
gwye-FEN-e-sin
Code⬆
NDC Code
0031- Richmond Division of Wyeth
0031-8724- Robitussin Mucus Plus Chest Congestion
0031-8724-12- 1 BOTTLE in 1 CARTON (0031-8724-12) > 118 mL in 1 BOTTLE
0113- L. Perrigo Company
0113-0061- good sense tussin mucus and chest congestion
0113-0061-26- 1 BOTTLE in 1 CARTON (0113-0061-26) > 118 mL in 1 BOTTLE
0113- L. Perrigo Company
0113-0061- good sense tussin mucus and chest congestion
0113-0061-34- 1 BOTTLE in 1 CARTON (0113-0061-34) > 237 mL in 1 BOTTLE
0113- L. Perrigo Company
0113-0325- Good Sense Mucus ER
0113-0325-66- 1 BOTTLE in 1 CARTON (0113-0325-66) > 14 TABLET, EXTENDED RELEASE in 1 BOTTLE
0113- L. Perrigo Company
0113-2061- tussin mucus plus chest congestion
0113-2061-26- 1 BOTTLE in 1 CARTON (0113-2061-26) > 118 mL in 1 BOTTLE
