Contraindicated in:
Use Cautiously in:
CV: peripheral edema, ARRHYTHMIA, bradycardia, chest pain, HF, hypotension, palpitations, syncope, tachycardia.
Derm: dermatitis, erythema multiforme, flushing, ↑ sweating, photosensitivity, pruritus/urticaria, rash, STEVENS-JOHNSON SYNDROME.
EENT: blurred vision, disturbed equilibrium, epistaxis, tinnitus.
Endo: gynecomastia, hyperglycemia.
GI: anorexia, constipation, diarrhea, dry mouth, dyspepsia, ↑ liver enzymes, nausea, vomiting.
GU: dysuria, nocturia, polyuria, sexual dysfunction, urinary frequency.
Hemat: anemia, leukopenia, thrombocytopenia.
Metab: weight gain.
MS: joint stiffness, muscle cramps.
Neuro: abnormal dreams, anxiety, confusion, dizziness, drowsiness, dysgeusia, headache, jitteriness, nervousness, paresthesia, psychiatric disturbances, tremor, weakness.
Resp: cough, dyspnea, shortness of breath.
Misc: gingival hyperplasia.
Drug-Drug:
Drug-Food:
(Generic available)
Cardene, Cardene IV
Therapeutic Classification: antianginals, antihypertensives
Pharmacologic Classification: calcium channel blockers
Absorption: Well absorbed following oral administration but extensively metabolized, resulting in ↓ bioavailability. IV administration results in complete bioavailability.
Distribution: Unknown.
Metabolism/Excretion: Mostly metabolized by the liver; 
10% excreted unchanged by kidneys.
Half-life: 2–4 hr.
NDC Code*