fen-oh-PROE-fen
Contraindicated in:
Use Cautiously in:
CV: edema, HF, MI, palpitations
Derm: DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (DRESS), pruritus, rash, STEVENS-JOHNSON SYNDROME (SJS), sweating
EENT: blurred vision, hearing loss, tinnitus
F and E: hyperkalemia
GI: dyspepsia, abdominal pain, constipation, diarrhea, GI BLEEDING, HEPATITIS, nausea, vomiting
GU: cystitis, dysuria, hematuria, renal failure
Hemat: prolonged bleeding time
Neuro: confusion, dizziness, drowsiness, headache, STROKE, tremor
Drug-drug:
Drug-Natural Products:
Rheumatoid Arthritis/Osteoarthritis
Mild to Moderate Pain
Therapeutic Classification: antirheumatics, nonopioid analgesics
Pharmacologic Classification: propionic acid derivatives, nonsteroidal anti inflammatory drugs nsaids
Absorption: Well absorbed from the GI tract.
Distribution: Unknown.
Protein Binding: >99%.
Half-Life: 3 hr.
| ROUTE | ONSET | PEAK | DURATION |
| PO (analgesic activity) | 15–30 min | 1–2 hr | 4–6 hr |
| PO (anti-inflammatory activity) | several days | 2–3 wk | unknown |
NDC Code