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Indications

REMS

Unlabeled Use:

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: ARRHYTHMIAS, HF, chest pain.

EENT: blurred vision, visual disturbances.

GI: anorexia, constipation, drug-induced hepatitis, nausea, stomach pain, vomiting.

Derm: rash.

Neuro: dizziness, anxiety, depression, fatigue, headache, tremor.

Interactions

Drug-Drug:

Drug-Food:

Availability

(Generic available)

Route/Dosage

Ventricular Tachycardia

Renal Impairment

Paroxysmal Supraventricular Tachycardia/Paroxysmal Atrial Fibrillation/Flutter

Atrial Fibrillation Conversion (unlabeled)

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antiarrhythmics (class IC)

Pharmacokinetics

Absorption: Well absorbed from the GI tract following oral administration.

Distribution: Widely distributed to tissues.

Metabolism/Excretion: Mostly metabolized by liver; 30% excreted unchanged by kidneys.

Half-life: 11–14 hr.

Canadian Brand Names

Tambocor

Time/Action Profile

(antiarrhythmic effects)

ROUTEONSETPEAKDURATION
POdaysdays–weeks12 hr

Patient/Family Teaching

Pronunciation

FLEK-a-nide

Code

NDC Code*