Vag (Adults and Children ≥12 yr): 1 applicatorful single dose.
US Brand Names⬆⬇
Gynazole-1
Action⬆⬇
Affects the permeability of the fungal cell wall, allowing leakage of cellular contents. Not active against bacteria.
Therapeutic effects:
Inhibited growth and death of susceptible Candida, with decrease in accompanying symptoms of vulvovaginitis (vaginal burning, itching, discharge).
Classifications⬆⬇
Therapeutic Classification: antifungals (vaginal)
Pharmacokinetics⬆⬇
Absorption: 2% is systemically absorbed following intravaginal administration.
Distribution: Unknown. Action is primarily local.
Metabolism/Excretion: Negligible with local application.
Half-Life: Not applicable.
Time/Action Profile⬆⬇
(plasma concentrations)
ROUTE
ONSET
PEAK
DURATION
Intravaginal
unknown
12–24 hr
unknown
Patient/Family Teaching⬆⬇
Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Therapy should be continued during menstrual period.
Advise patient to avoid using tampons while using this product.
Instruct patient on proper use of vaginal applicator. Medication should be inserted high into the vagina at bedtime. Instruct patient to remain recumbent for at least 30 min after insertion. Advise use of sanitary napkins to prevent staining of clothing or bedding.
Advise patient to consult health care professional regarding intercourse during therapy. Vaginal medication may cause minor skin irritation in sexual partner. Advise patient to refrain from sexual contact during therapy. Advise patient that this medication may weaken latex or rubber contraceptive products. Another method of contraception should be used during treatment.
Advise patient to report to health care professional increased skin irritation or lack of response to therapy. A second course may be necessary if symptoms persist.
Advise patient to dispose of applicator after each use.
Inform patient that therapeutic response is usually seen after 1 wk.
Pronunciation⬆⬇
byoo-toe-KON-a-zole
Code⬆
NDC Code
45802- Perrigo New York Inc
45802-396- gynazole 1
45802-396-01- 1 TUBE, WITH APPLICATOR in 1 CARTON (45802-396-01) > 5.8 g in 1 TUBE, WITH APPLICATOR
45802- Perrigo New York Inc
45802-396- gynazole 1
45802-396-02- 1 TUBE, WITH APPLICATOR in 1 CARTON (45802-396-02) > 5.8 g in 1 TUBE, WITH APPLICATOR
