Contraindicated in:
Use Cautiously in:
CV: ARRHYTHMIAS, chest pain, HF, hypotension, palpitations, peripheral edema, syncope, tachycardia.
Derm: ↑sweating, dermatitis, ERYTHEMA MULTIFORME, flushing, photosensitivity, pruritus/urticaria, rash, STEVENS-JOHNSON SYNDROME (SJS).
EENT: blurred vision, disturbed equilibrium, epistaxis, tinnitus.
Endo: gynecomastia, hyperglycemia.
GI: ↑liver enzymes, anorexia, constipation, diarrhea, dry mouth, dyspepsia, nausea, vomiting.
GU: dysuria, nocturia, polyuria, sexual dysfunction, urinary frequency.
Hemat: anemia, leukopenia, thrombocytopenia.
Metab: ↑weight.
MS: joint stiffness, muscle cramps.
Neuro: abnormal dreams, anxiety, confusion, dizziness, drowsiness, dysgeusia, headache, nervousness, paresthesia, psychiatric disturbances, tremor, weakness.
Resp: cough, dyspnea.
Misc: gingival hyperplasia.
Drug-Drug:
Drug-Natural Products:
Drug-Food:
Hepatic Impairment
Therapeutic Classification:subarachnoid hemorrhage therapy agents
Pharmacologic Classification: calcium channel blockers
Absorption: Well absorbed following oral administration but undergoes first-pass metabolism, resulting in ↓ bioavailability.
Distribution: Crosses the blood-brain barrier; remainder of distribution unknown.
Protein Binding: >95%.
Metabolism/Excretion: Mostly metabolized by the liver; 
10% excreted unchanged by kidneys.
Half-life: 1–2 hr.
NDC Code*