May ↓ absorption of any medications that have pH-dependent absorption (↑ gastric pH); administer other oral medications ≥2 hr before or after sodium zirconium cyclosilicate.
Availability⬆⬇
Oral suspension: 5 g/pkt; 10 g/pkt
Route/Dosage⬆⬇
PO (Adults ): 10 g 3 times daily in water for up to 48 hr, then 10 g once daily (if treatment continued beyond 48 hr); may titrate chronic therapy in increments of 5 g at 1–wk intervals (recommended maintenance dose range = 5–15 g once daily).
US Brand Names⬆⬇
Lokelma
Action⬆⬇
Exchanges hydrogen and sodium ions for potassium ions in the intestine.