clascoterone

Contraindicated in:

None.

Use Cautiously in:

OB: Safety not established in pregnancy;
Lactation: Safety not established in breastfeeding;
Pedi: Children <12 yr (safety and effectiveness not established); children may be more susceptible to hypothalamic-pituitary-adrenal (HPA) axis suppression.

Adv. Reactions/Side Effects ⬆ ⬇

Derm: dry skin, erythema, pruritus

Endo: HPA axis suppression

Interactions ⬆ ⬇

Drug-drug:

None reported.

Availability ⬆ ⬇

Route/Dosage ⬆ ⬇

(Adults and Children ≥12 yr): Apply to affected area(s) twice daily.

US Brand Names ⬆ ⬇

Action ⬆ ⬇

Acts as an androgen receptor inhibitor.

Therapeutic effects:

Reduction in inflammatory and noninflammatory acne lesions.

Classifications ⬆ ⬇

Therapeutic Classification: antiacne agents

Pharmacologic Classification: androgen receptor inhibitors

Pharmacokinetics ⬆ ⬇

Absorption: Does undergo systemic absorption (extent unknown).

Distribution: Unknown.

Metabolism/Excretion: Primarily metabolized in liver to several metabolites. Excretion pathway unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

(diminution of acne)

ROUTE	ONSET	PEAK	DURATION
Topical	unknown	up to 12 wk	unknown

Patient/Family Teaching ⬆ ⬇

Instruct patient in proper technique for applying cream. Avoid applying to cuts, abrasions, eczematous or sunburned skin. Advise patient to read Patient Information before starting and with each Rx refill in case of changes.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and consult health care professional before taking any new medications.
Rep: Advise females of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Pronunciation ⬆ ⬇

Code ⬆

NDC Code

47335- Sun Pharmaceutical Industries, Inc.
- 47335-994- Winlevi
  - 47335-994-36- 1 TUBE in 1 CARTON (47335-994-36) / 60 g in 1 TUBE

47335- Sun Pharmaceutical Industries, Inc.
- 47335-994- Winlevi
  - 47335-994-94- 12 CARTON in 1 CASE (47335-994-94) / 1 TUBE in 1 CARTON (47335-994-40) / 2 g in 1 TUBE

58175- Wavelength Enterprises Ltd
- 58175-0650-
  - 58175-0650-0- 1 BAG in 1 DRUM (58175-0650-0) / 5 kg in 1 BAG

60722- zhejiang xianju pharmaceutical co., Ltd.
- 60722-3024-
  - 60722-3024-1- 1 kg in 1 DRUM (60722-3024-1)

60722- zhejiang xianju pharmaceutical co., Ltd.
- 60722-3024-
  - 60722-3024-2- 2.5 kg in 1 DRUM (60722-3024-2)

73377- AX Pharmaceutical Corp
- 73377-304-
  73377-304-01- 500 g in 1 JAR (73377-304-01)

section name header

Indications ⬇

Contraind./Precautions ⬆ ⬇