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Indications ⬇

REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

GU: irritation, vulvovaginal burning

Interactions ⬆ ⬇

Drug-drug:

Availability ⬆ ⬇

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

1–Day, Monistat-1Day, Vagistat-1

Action ⬆ ⬇

  • Affects the permeability of the fungal cell wall, allowing leakage of cellular contents. Not active against bacteria.
Therapeutic effects:
  • Inhibited growth and death of susceptible Candida, with decrease in accompanying symptoms of vulvovaginitis (vaginal burning, itching, discharge).

Classifications ⬆ ⬇

Therapeutic Classification: antifungals (vaginal)

Pharmacokinetics ⬆ ⬇

Absorption: Minimal through intact skin.

Distribution: Unknown. Action is primarily local.

Metabolism/Excretion: Negligible with local application.

Half-Life: Not applicable.

Time/Action Profile ⬆ ⬇

ROUTEONSETPEAKDURATION
Intravagunknownunknownunknown

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

tye-oh-KON-a-zole

Code ⬆

NDC Code