Lactation: Use cautiously, clindamycin may enter breast milk, consider discontinuing drug or breast-feeding taking into account importance of drug to mother;
Pedi: Safe and effective use in children <12 yr not established.
Absorption: Some absorption of clindamycin follows topical administration.
Distribution: Unknown.
Metabolism/Excretion: Unknown.
Half-Life: Unknown.
Time/Action Profile⬆⬇
(improvement in acne)
ROUTE
ONSET
PEAK
DURATION
Topical
days-wks
unknown
unknown
Patient/Family Teaching⬆⬇
Instruct patient on correct procedure for application. Advise patient not to apply more than pea size amount or more frequently than once daily; may increase irritation.
Inform patient medication may cause erythema, scaling, itching, burning or stinging. Use of products that are drying or abrasive will increase skin irritation.
Advise patient to use sunscreen daily and protective clothing and to avoid exposure to sunlight, sunlamps, and weather extremes (wind or cold) to prevent photosensitivity reactions or skin irritation.
Caution patient to notify health care professional if fever and diarrhea occur, especially if stool contains blood, pus, or mucus. Advise patient to stop medication and not to treat diarrhea without consulting health care professional. May occur up to several wk after discontinuation of medication.
Notify health care professional of medication if surgery with general anesthesia is planned.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Advise patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.