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Indications ⬇

REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

Derm: ↑hair loss (shampoo)

Local: burning, itching, local hypersensitivity reactions, redness, stinging

Interactions ⬆ ⬇

Drug-drug:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Ketodan, Nizoral, Nizoral A-D, Xolegel

Action ⬆ ⬇

  • Affects the synthesis of the fungal cell wall.
Therapeutic effects:
  • Decreased symptoms of fungal infection.

Classifications ⬆ ⬇

Therapeutic Classification: antifungals

Pharmacologic Classification: imidazoles

Pharmacokinetics ⬆ ⬇

Absorption: Minimal absorption through intact skin.

Distribution: If absorption occurs, widely distributed; crosses the placenta; enters breast milk. Action after topical administration is primarily local.

Metabolism/Excretion: If absorbed, partially metabolized by the liver then excreted in feces via biliary excretion.

Half-Life: If absorbed, 8 hr.

Canadian Brand Names ⬆ ⬇

Ketoderm

Time/Action Profile ⬆ ⬇

(resolution of symptoms/lesions)

ROUTEONSETPEAKDURATION
Topicalunknownunknownunknown

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

kee-toe-KOE-na-zole

Code ⬆

NDC Code