section name header

Indications ⬇

BEERS REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

Derm: allergic dermatitis

GI: constipation, diarrhea, GI BLEEDING, heartburn, nausea, vomiting

Hemat: AGRANULOCYTOSIS, anemia

Neuro: dizziness, drowsiness

Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANGIOEDEMA)

Interactions ⬆ ⬇

Drug-drug:

Drug-Natural Products:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Lorzone, Parafon Forte DSC

Action ⬆ ⬇

  • Skeletal muscle relaxation, probably due to CNS depression.
Therapeutic effects:
  • Skeletal muscle relaxation with decreased discomfort.

Classifications ⬆ ⬇

Therapeutic Classification: skeletal muscle relaxants (centrally acting)

Pharmacokinetics ⬆ ⬇

Absorption: Readily absorbed after oral administration.

Distribution: Unknown.

Metabolism/Excretion: Mostly metabolized by the liver; <1% excreted unchanged in urine.

Half-Life: 1.1 hr.

Time/Action Profile ⬆ ⬇

(skeletal muscle effects)

ROUTEONSETPEAKDURATION
POwithin 1 hr1–2 hr3–4 hr

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

klor-ZOX-a-zohn

Code ⬆

NDC Code