section name header

Indications ⬇

BEERS REMS


Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

CV: peripheral edema

Derm: photosensitivity

EENT: abnormal vision, altered sense of smell, ear pain, epistaxis, hearing sensitivity, ocular pain

GI: abdominal pain, anorexia, colitis, dyspepsia, nausea

GU: dysmenorrhea

Neuro: abnormal thinking, amnesia, anxiety, behavior changes, COMPLEX SLEEP BEHAVIORS (INCLUDING SLEEP DRIVING, SLEEP WALKING, OR ENGAGING IN OTHER ACTIVITIES WHILE SLEEPING), depersonalization, dizziness, drowsiness, hallucinations, headache, hyperesthesia, impaired memory (briefly following dose), impaired psychomotor function (briefly following dose), malaise, nightmares, paresthesia, tremor, vertigo, weakness

Misc: fever

Interactions ⬆ ⬇

Drug-drug:

Drug-Natural Products:

Drug-Food:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

Hepatic Impairment

US Brand Names ⬆ ⬇

Sonata

Action ⬆ ⬇

  • Produces CNS depression by binding to GABA receptors in the CNS.
  • Has no analgesic properties.
Therapeutic effects:
  • Induction of sleep.

Classifications ⬆ ⬇

Therapeutic Classification: sedative/hypnotics

Pharmacokinetics ⬆ ⬇

Absorption: Rapidly absorbed following oral administration.

Distribution: Well distributed to tissues.

Metabolism/Excretion: Extensively metabolized in the liver (mostly by aldehyde oxidase and some by the CYP3A4 isoenzyme).

Half-Life: 1 hr.

Contr. Subst. Schedule ⬆ ⬇

Schedule IV (C-IV)

Time/Action Profile ⬆ ⬇

ROUTEONSETPEAKDURATION
POwithin minunknown3–4 hr

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

za-LEP-lon

Code ⬆

NDC Code