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Indications

REMS


Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

EENT: conjunctival hyperemia, dry eye, eye pruritus, hyperpigmentation of eyelids, macular edema, periorbital erythema, permanent pigmentation of the iris

Misc: hypersensitivity reactions

Interactions

Drug-drug:

Availability

(Generic available)

Route/Dosage

US Brand Names

Latisse

Action

  • Increases the percent of hair in eyelashes and prolongs the duration of growth phase.
Therapeutic effects:
  • Increases eyelash growth, improving length, thickness, and darkness.

Classifications

Therapeutic Classification: hair regrowth stimulants

Pharmacologic Classification: prostaglandins

Pharmacokinetics

Absorption: Minimal systemic absorption.

Distribution: Small amounts absorbed are widely distributed.

Metabolism/Excretion: Highly metabolized; 67% excreted in urine, 25% in feces mostly as metabolites.

Half-Life: 45 min.

Time/Action Profile

(improvement in eyelash growth)

ROUTEONSETPEAKDURATION
Topical2 mos4 mos4 wk or more*

*Following discontinuation.

Patient/Family Teaching

Pronunciation

bi-MAT-o-prost

Code

NDC Code