Primary Nocturnal Enuresis
- PO (Adults and Children ≥6 yr): 0.2 mg at bedtime; may be titrated up to 0.6 mg at bedtime to achieve desired response.
- SL (Adults and Children ): 120 mcg 1 hr before bedtime; may be titrated up to 360 mcg at bedtime to achieve desired response.
Diabetes Insipidus
- PO (Adults and Children ): 0.05 mg twice daily; adjusted as needed (usual range: 0.1–1.2 mg/day for adults or 0.1–0.8 mg/day for children in 2–3 divided doses).
- SL (Adults and Children ): 60 mcg 3 times daily; adjusted as needed (usual range: 120–720 mcg/day in 2–3 divided doses).
- (Adults and Children ≥12 yr): DDAVP: 5–40 mcg (0.0.05–0.4 mL) in 1–3 divided doses.
- (Children 3 mo–12 yr): DDAVP: 5–30 mcg (0.05–0.3 mL) in 1–2 divided doses.
- SC IV (Adults and Children ≥12 yr): 2–4 mcg/day in 2 divided doses.
- SC IV (Children <12 yr): 0.1–1 mcg/day in 1–2 divided doses.
Hemophilia A/von Willebrand Disease
- IV (Adults and Children >3 mo): 0.3 mcg/kg, repeated as needed.
Nocturia
- SL (Adults ): Women: 27.7 mcg 1 hr before bedtime; Men: 55.3 mcg 1 hr before bedtime.
