(Adults and Children ≥6 mo): Apply 1 mm layer to affected wound surface with each wound dressing change. Continue until wound heals.
US Brand Names⬆⬇
Filsuvez
Action⬆⬇
A botanical drug substance composed of a mixture of the following pentacyclic triterpenes: betulin, betulinic acid, lupeol, erythrodiol, and oleanolic acid. Its mechanism of benefit in dystrophic and junctional epidermolysis bullosa is unknown.
Therapeutic effects:
Closure of wounds.
Classifications⬆⬇
Therapeutic Classification: none assigned
Pharmacokinetics⬆⬇
Absorption: Undergoes minimal systemic absorption following topical administration.
Distribution: Unknown.
Protein Binding: >99.9%.
Metabolism/Excretion: Betulin may be metabolized by the liver via the CYP3A isoenzyme. Excretion pathway unknown.
Half-Life: Unknown.
Time/Action Profile⬆⬇
ROUTE
ONSET
PEAK
DURATION
Topical
unknown
unknown
unknown
Patient/Family Teaching⬆⬇
Explain purpose and side effects of medication to patient. Advise patient to read Patient Information before starting therapy.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult health care professional before taking other medications.
Explain that if hives, dermatitis, or other skin changes occur, immediately discontinue therapy and notify health care professional.
Rep: Advise females of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Pronunciation⬆⬇
BERCHtri-TER-peens
Code⬆
NDC Code
10122- Chiesi USA, Inc.
10122-310- FILSUVEZ
10122-310-02- 1 TUBE in 1 CARTON (10122-310-02) / 23.4 g in 1 TUBE (10122-310-01)
71161- Synergy Health
71161-152-
71161-152-01- 1 TUBE in 1 CARTON (71161-152-01) / 23.4 g in 1 TUBE
76431- Amryt Pharmaceuticals DAC
76431-310- FILSUVEZ
76431-310-01- 1 TUBE in 1 CARTON (76431-310-01) / 23.4 g in 1 TUBE
