dess-IP-ra-meen
Contraindicated in:
Use Cautiously in:
May ↑ risk of suicide attempt/ideation, especially during early treatment or dose adjustment; risk may be greater in children or adolescents;
CV: hypotension, ARRHYTHMIAS, ECG changes
Derm: photosensitivity
EENT: blurred vision, dry eyes
Endo: changes in blood glucose, gynecomastia
F and E: hyponatremia, SIADH
GI: constipation, dry mouth, hepatitis, paralytic ileus
GU: ↓libido, urinary retention
Hemat: blood dyscrasias
Neuro: drowsiness, fatigue, SUICIDAL THOUGHTS/BEHAVIORS
Drug-drug:
Drug-Natural Products:
Absorption: Well absorbed from the GI tract.
Distribution: Widely distributed.
Protein Binding: 90–92%.
Half-Life: 12–27 hr.
Advise patient, family, and caregivers to look for suicidality, especially during early therapy or dose changes. Notify health care provider immediately if thoughts about suicide or dying, attempts to commit suicide, new or worse depression or anxiety, agitation or restlessness, panic attacks, insomnia, new or worse irritability, aggressiveness, acting on dangerous impulses, mania, or other changes in mood or behavior occur.
NDC Code