ess-sit-AL-o-pram
BEERS REMS
Contraindicated in:
Use Cautiously in:
May ↑ risk of suicide attempt/ideation especially during early treatment or dose adjustment; this risk appears to be greater in adolescents or children
;Derm: sweating
Endo: SIADH
F and E: hyponatremia
GI: diarrhea, nausea, abdominal pain, constipation, dry mouth, indigestion
GU: ↓libido, delayed/absent orgasm, ejaculatory delay/failure, erectile dysfunction
Hemat: BLEEDING
Neuro: insomnia, dizziness, drowsiness, fatigue, NEUROLEPTIC MALIGNANT SYNDROME, SUICIDAL THOUGHTS/BEHAVIORS
Misc: SEROTONIN SYNDROME
Drug-drug:
Drug-Natural Products:
Major Depressive Disorder
Hepatic Impairment
Generalized Anxiety Disorder
Hepatic Impairment
Therapeutic Classification: antidepressants
Pharmacologic Classification: selective serotonin reuptake inhibitors ssris
Absorption: 80% absorbed following oral administration.
Distribution: Widely distributed to tissues.
Half-Life: 27–32 hr (↑ in older adults and hepatic impairment).
Advise patient, family, and caregivers to look for suicidality, especially during early therapy or dose changes. Notify health care provider immediately if thoughts about suicide or dying, attempts to commit suicide, new or worse depression or anxiety, agitation or restlessness, panic attacks, insomnia, new or worse irritability, aggressiveness, acting on dangerous impulses, mania, or other changes in mood or behavior.
NDC Code
