Renal Allograft Rejection Prevention
- PO IV (Adults and Children ): 3–5 mg/kg/day initially; maintenance dose 1–3 mg/kg/day.
Rheumatoid Arthritis
- PO IV (Adults and Children ): 1 mg/kg/day for 6–8 wk; ↑ by 0.5 mg/kg/day every 4 wk until response or up to 2.5 mg/kg/day; then ↓ by 0.5 mg/kg/day every 4–8 wk to minimal effective dose.
Inflammatory Bowel Disease (Crohn Disease or Ulcerative Colitis) (unlabeled use)
- PO (Adults and Children ): 50 mg once daily; may ↑ by 25 mg/day every 1–2 wk as tolerated to target dose of 2–3 mg/kg/day.
