- IV (Adults ): 1500 mg/m2 on Days 1, 3 and 5 of every 21-day cycle.
- IV (Children ≥1 yr): 650 mg/m2/day for first 5 days of every 21-day cycle.
High Alert
Contraindicated in:
Use Cautiously in:
Hemat: anemia, leukopenia, neutropenia, thrombocytopenia
Neuro: coma, craniospinal demyelination, dizziness, drowsiness, headache, paresthesia, status epilepticus, amnesia, ataxia, balance disorder, dysgeusia, neuropathy, tremor
Drug-drug:
Absorption: IV administration results in complete bioavailability. Intracellular conversion is required for activation of prodrug.
Distribution: Extensively distributed.
Half-Life: Unknown.
NDC Code
